{"id":13013,"date":"2022-09-24T09:00:05","date_gmt":"2022-09-24T07:00:05","guid":{"rendered":"https:\/\/world-heart-federation.org\/?post_type=news&#038;p=13013"},"modified":"2022-11-08T15:33:26","modified_gmt":"2022-11-08T14:33:26","slug":"renewing-our-commitment-to-the-global-call-to-action-on-familial-hypercholesterolemia","status":"publish","type":"news","link":"https:\/\/world-heart-federation.org\/news\/renewing-our-commitment-to-the-global-call-to-action-on-familial-hypercholesterolemia\/","title":{"rendered":"Renewing Our Commitment to the Global Call to Action on Familial Hypercholesterolemia"},"content":{"rendered":"<p><span class=\"TextRun SCXW4189813 BCX0\" lang=\"EN-GB\" xml:lang=\"EN-GB\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW4189813 BCX0\">Familial Hypercholesterolemia <\/span><span class=\"NormalTextRun SCXW4189813 BCX0\">or FH <\/span><span class=\"NormalTextRun SCXW4189813 BCX0\">is a genetic disorder that causes high <\/span><span class=\"NormalTextRun SCXW4189813 BCX0\">levels of cholesterol from birth. The condition affects 1 in 311 people or approximately 25 million of individuals worldwide<\/span><span class=\"NormalTextRun SCXW4189813 BCX0\">. Untreated, lifelong exposure to <\/span><span class=\"NormalTextRun SCXW4189813 BCX0\">elevated concentrations of low-density lipoprotein (LDL) cholesterol leads to premature <\/span><span class=\"NormalTextRun SCXW4189813 BCX0\">heart disease and deaths.<\/span><\/span><span class=\"EOP SCXW4189813 BCX0\" data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:240,&quot;335559740&quot;:360}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">In 1998, the World Health Organization (WHO) formally recognized FH as a global public health issue and published a set of recommendations to address its burden. Two decades later, implementation of the WHO recommendations has remained largely insufficient in many countries and regions. In fact, nearly 90% of individuals living with FH remain undiagnosed and therefore untreated, despite the fact that established evidence shows that early diagnosis and treatment of FH are critical to averting further premature cardiovascular disease morbidity and mortality.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:240,&quot;335559740&quot;:360}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">In 2020, representatives from the global FH community launched a <\/span><a href=\"https:\/\/jamanetwork.com\/journals\/jamacardiology\/article-abstract\/2758279\"><span data-contrast=\"none\">Global Call to Action<\/span><\/a><span data-contrast=\"auto\"> and issued a set of revised recommendations to reduce the clinical and public health burden of familial hypercholesterolemia globally. On <\/span><b><span data-contrast=\"auto\">FH Awareness Day<\/span><\/b><span data-contrast=\"auto\">, the World Heart Federation (WHF) urges governments, the World Health Organization, and the global health community to:<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:240,&quot;335559740&quot;:360}\">\u00a0<\/span><\/p>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559684&quot;:-2,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" data-aria-posinset=\"1\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">Raise awareness<\/span><\/b><span data-contrast=\"auto\"> of FH as a global public health issue<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559684&quot;:-2,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Actively <\/span><b><span data-contrast=\"auto\">screen, test, and diagnose<\/span><\/b><span data-contrast=\"auto\"> for individuals with FH by implementing systematic cascade screening or universal screening for children<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:240,&quot;335559740&quot;:360}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559684&quot;:-2,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Manage and<\/span><b><span data-contrast=\"auto\"> treat FH<\/span><\/b><span data-contrast=\"auto\"> patients to prevent further premature heart disease and deaths<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:240,&quot;335559740&quot;:360}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559684&quot;:-2,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" data-aria-posinset=\"1\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">Guarantee care for severe and homozygous FH<\/span><\/b><span data-contrast=\"auto\"> patients since they require specialized guidelines and care<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:240,&quot;335559740&quot;:360}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559684&quot;:-2,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" data-aria-posinset=\"1\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">Develop family-based care plans<\/span><\/b><span data-contrast=\"auto\"> for people living with FH and ensure opportunities for patient involvement as well as shared decision-making<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:240,&quot;335559740&quot;:360}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559684&quot;:-2,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Establish and <\/span><b><span data-contrast=\"auto\">fund FH registries<\/span><\/b><span data-contrast=\"auto\"> to collect relevant data, identify gaps, inform best practices, and monitor progress<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:240,&quot;335559740&quot;:360}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559684&quot;:-2,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Conduct <\/span><b><span data-contrast=\"auto\">research and implement<\/span><\/b><span data-contrast=\"auto\"> FH programmes to improve care<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:240,&quot;335559740&quot;:360}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559684&quot;:-2,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" data-aria-posinset=\"1\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">Understand the value and costs<\/span><\/b><span data-contrast=\"auto\"> of FH interventions\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:240,&quot;335559740&quot;:360}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559684&quot;:-2,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" data-aria-posinset=\"1\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">Advocate<\/span><\/b><span data-contrast=\"auto\"> for the implementation of the above recommendations!<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:240,&quot;335559740&quot;:360}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><span data-contrast=\"auto\">In light of the continued need to raise awareness of FH and identify gaps as well as opportunities, the World Heart Federation has conducted, in partnership with FH Europe, an international survey to map the state of FH around the world. The <\/span><a href=\"https:\/\/world-heart-federation.org\/resource\/familial-hypercholesterolemia-country-mapping-survey-preliminary-analysis\/\"><span data-contrast=\"none\">preliminary analysis of the data<\/span><\/a><span data-contrast=\"auto\"> concurred with well-established evidence: FH remains a widely underdiagnosed and undertreated condition across all countries and regions. Fortunately, the initial findings also suggest that many countries have initiated more actions to address FH at the national level.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:240,&quot;335559740&quot;:360}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Lastly, on 14 October 2022, WHF will launch its updated WHF Roadmap on Cholesterol, which will include the latest evidence on the diagnosis and management of FH, as well as lessons learnt since 2017. WHF roadmaps are frameworks that help identify roadblocks as well as potential solutions to the effective prevention, detection, and treatment of cardiovascular disease.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:240,&quot;335559740&quot;:360}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Please visit our <\/span><a href=\"https:\/\/world-heart-federation.org\/what-we-do\/cholesterol\/familial-hypercholesterolemia\/\"><span data-contrast=\"none\">FH webpage<\/span><\/a><span data-contrast=\"auto\"> for more information and resources.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:240,&quot;335559740&quot;:360}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Familial Hypercholesterolemia or FH is a genetic disorder that causes high levels of cholesterol from birth. The condition affects 1 in 311 people or approximately 25 million of individuals worldwide. Untreated, lifelong exposure to elevated concentrations of low-density lipoprotein (LDL) cholesterol leads to premature heart disease and deaths.\u00a0 In 1998, the World Health Organization (WHO) [&hellip;]<\/p>\n","protected":false},"featured_media":13014,"template":"","meta":{"_relevanssi_hide_post":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":""},"event":[],"project-campaign":[],"topic":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Renewing Our Commitment to the Global Call to Action on Familial Hypercholesterolemia - World Heart Federation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/world-heart-federation.org\/news\/renewing-our-commitment-to-the-global-call-to-action-on-familial-hypercholesterolemia\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Renewing Our Commitment to the Global Call to Action on Familial Hypercholesterolemia - World Heart Federation\" \/>\n<meta property=\"og:description\" content=\"Familial Hypercholesterolemia or FH is a genetic disorder that causes high levels of cholesterol from birth. The condition affects 1 in 311 people or approximately 25 million of individuals worldwide. Untreated, lifelong exposure to elevated concentrations of low-density lipoprotein (LDL) cholesterol leads to premature heart disease and deaths.\u00a0 In 1998, the World Health Organization (WHO) [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/world-heart-federation.org\/news\/renewing-our-commitment-to-the-global-call-to-action-on-familial-hypercholesterolemia\/\" \/>\n<meta property=\"og:site_name\" content=\"World Heart Federation\" \/>\n<meta property=\"article:modified_time\" content=\"2022-11-08T14:33:26+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/world-heart-federation.org\/wp-content\/uploads\/FH-Awareness-Day.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"4000\" \/>\n\t<meta property=\"og:image:height\" content=\"2670\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/world-heart-federation.org\/news\/renewing-our-commitment-to-the-global-call-to-action-on-familial-hypercholesterolemia\/\",\"url\":\"https:\/\/world-heart-federation.org\/news\/renewing-our-commitment-to-the-global-call-to-action-on-familial-hypercholesterolemia\/\",\"name\":\"Renewing Our Commitment to the Global Call to Action on Familial Hypercholesterolemia - World Heart Federation\",\"isPartOf\":{\"@id\":\"https:\/\/world-heart-federation.org\/#website\"},\"datePublished\":\"2022-09-24T07:00:05+00:00\",\"dateModified\":\"2022-11-08T14:33:26+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/world-heart-federation.org\/news\/renewing-our-commitment-to-the-global-call-to-action-on-familial-hypercholesterolemia\/#breadcrumb\"},\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/world-heart-federation.org\/news\/renewing-our-commitment-to-the-global-call-to-action-on-familial-hypercholesterolemia\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/world-heart-federation.org\/news\/renewing-our-commitment-to-the-global-call-to-action-on-familial-hypercholesterolemia\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/world-heart-federation.org\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"News\",\"item\":\"https:\/\/world-heart-federation.org\/news\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Renewing Our Commitment to the Global Call to Action on Familial Hypercholesterolemia\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/world-heart-federation.org\/#website\",\"url\":\"https:\/\/world-heart-federation.org\/\",\"name\":\"World Heart Federation\",\"description\":\"Cardiovascular Health for Everyone\",\"publisher\":{\"@id\":\"https:\/\/world-heart-federation.org\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/world-heart-federation.org\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-GB\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/world-heart-federation.org\/#organization\",\"name\":\"World Heart Federation\",\"url\":\"https:\/\/world-heart-federation.org\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/world-heart-federation.org\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/world-heart-federation.org\/wp-content\/uploads\/2021\/02\/main-logo.svg\",\"contentUrl\":\"https:\/\/world-heart-federation.org\/wp-content\/uploads\/2021\/02\/main-logo.svg\",\"width\":183,\"height\":59,\"caption\":\"World Heart Federation\"},\"image\":{\"@id\":\"https:\/\/world-heart-federation.org\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Renewing Our Commitment to the Global Call to Action on Familial Hypercholesterolemia - World Heart Federation","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/world-heart-federation.org\/news\/renewing-our-commitment-to-the-global-call-to-action-on-familial-hypercholesterolemia\/","og_locale":"en_GB","og_type":"article","og_title":"Renewing Our Commitment to the Global Call to Action on Familial Hypercholesterolemia - World Heart Federation","og_description":"Familial Hypercholesterolemia or FH is a genetic disorder that causes high levels of cholesterol from birth. 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