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Multi-National Studies

Data availability is crucial to advance scientific knowledge, diagnosis and management of cardiovascular diseases (CVDs). The World Heart Observatory is compiling high quality registries and epidemiological studies on various forms of CVDs from around the world. In the coming days, users will enable to explore the data from these studies through interactive visualisations as well as have access to the original studies and publications.

Keep an eye out on this space and our social media channels for updates.

Details on the INTERASPIRE study are now available below!

Our Multi-National Studies

The Cohorts Consortium of Latin America and the Caribbean


Study type

Consortium / pooled analysis of population-based cohort studies

Start: 2020

End: Ongoing


Primary objective

To examine the association between cardio-metabolic risk factors (blood pressure, glucose, lipids) and non-fatal and fatal cardiovascular outcomes (stroke, myocardial infarction).

Lead institution

Universidad Peruana Cayetano Heredia, Peru (corresponding author institution); Imperial College London, UK (hosting operations)

Principal investigator

J Jaime Miranda (Universidad Peruana Cayetano Heredia, Peru)

Global Health and Population Project on Access to Care for Cardiometabolic Diseases


Study type

Population-based survey data analysis

Start: 2005

End: 2023


Primary objective

HPACC was established to meet the clear need for answers to key health policy and clinical questions relating to cardiometabolic diseases globally.

Lead institution

Not specified

Principal investigator

Jennifer Manne-Goehler

The International Action on Secondary Prevention through Intervention to Reduce Event


Study type

Observational international survey

Start: 2020

End: 2023


Primary objective

Adults with known cardiovascular conditions, such as coronary heart disease, are at a higher risk for further cardiovascular events. Several secondary prevention guidelines and recommendations have been created, which emphasize evidence-based lifestyle and pharmacological treatment. The World Heart Federation has also recently updated its secondary prevention roadmap, detailing strategies for improving secondary prevention at all levels of the health system.INTERASPIRE is an international study covering 14 countries across the 6 World Health Organization (WHO) regions. It is designed to measure if the guideline standards for secondary prevention and cardiac rehabilitation are being achieved in a timely manner in patients with coronary heart disease.

INTERASPIRE demonstrates inadequate and heterogenous international implementation of guideline standards for secondary prevention in the first year after hospitalization for coronary heart disease and shows geographic and sex disparity. Investment aiming to reduce between-country and between-individual variability in secondary prevention will promote equity in global efforts to reduce the burden of coronary heart disease.

INTERASPIRE. Coronary Heart Disease Patients: 14 Countries from all 6 WHO Regions. 4548 participants Enrolled 2023 - 2023. Secondary Prevention Guideline Targets Assessed a Median 1 Year after Index Event. 13% Active Smoking. 67% not at PA Target. 41% Central Obesity. 67% Dysglycaemia (DM or IFG). 83% LDLc >= 1.4 mmol/L. 61% BP >= 130/80 mmHg. 91% Did Not Attend* Cardiac Rehabilitation.

For more information on the study, please refer to the information below. Further interactive data visualizations to be available soon!


Lead institution

Multiple CVD societies

Principal investigator

David Wood

 

Prospective Urban Rural Epidemiology Study


Study type

Observational prospective cohort study

Start: 2002

End: 2030


Primary objective

To examine the relationship between societal influences and prevalence of risk factors and chronic noncommunicable diseases measured at baseline. Societal determinants are measured by an index of measures from four domains: built environment, food and nutrition policy, psychosocial and socioeconomic factors, and tobacco. The study also examines how these societal determinants influence the incidence of chronic noncommunicable disease events and changes in rates of selected risk factors over time.

Lead institution

Population Health Research Institute (PHRI), McMaster University, Hamilton Health Sciences

Principal investigator

Salim Yusuf

Rheumatic Heart Disease Registry


Study type

Observational registry

Start: 2010

End: 2016


Primary objective

To document the clinical and echocardiographic characteristics of patients at presentation and to document disease progression and treatment practices over a two-year follow-up, with particular reference to adherence to secondary prophylaxis and oral anticoagulation regimens.

Lead institution

Population Health Research Institute (PHRI)

Principal investigator

Ganesan Karthikeyan

BuRden of ChAgas dISEase in the contemporary world


Study type

Meta-analysis

Start: Not specified

End: Not specified


Primary objective

The RAISE project aims to reassess the burden of Chagas disease and Chagas disease cardiomyopathy. Using a multidimensional approach, the project seeks to refine estimates of Chagas disease-related deaths, conduct systematic reviews on seroprevalence and prevalence of clinical forms, enhance existing modeling frameworks, and calculate the global economic burden, including healthcare expenditures and access to services.

Lead institution

World Heart Federation

Principal investigator

Antonio Ribeiro
With the support of